| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 02-Sep-06 | vs North Texas (112) | 56-7 | Won | -2.00 | 0.00 |
| 09-Sep-06 | vs Ohio State (1) | 7-24 | Lost | 3.48 | 0.00 |
| 16-Sep-06 | at Rice (58) | 52-7 | Won | 0.18 | 0.16 |
| 23-Sep-06 | vs Iowa St (97) | 37-14 | Won | -1.28 | 0.00 |
| 07-Oct-06 | vs Oklahoma (17) | 28-10 | Won | 0.99 | 0.97 |
| 14-Oct-06 | vs Baylor (77) | 63-31 | Won | -0.76 | 0.00 |
| 21-Oct-06 | at Nebraska (42) | 22-20 | Won | 0.68 | 0.66 |
| 28-Oct-06 | at Texas Tech (52) | 35-31 | Won | 0.24 | 0.23 |
| 04-Nov-06 | vs Oklahoma St (61) | 36-10 | Won | -0.38 | 0.00 |
| 11-Nov-06 | at Kansas St (69) | 42-45 | Lost | -0.06 | -1.00 |
| 24-Nov-06 | vs Texas A&M (39) | 7-12 | Lost | 0.27 | -1.00 |
A red opponent rating indicates modification according to home field advantage (0.24).