| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 31-Aug-06 | vs Boston College (15) | 24-31 | Lost | 0.8206 | -0.4098 |
| 09-Sep-06 | at Michigan (1) | 17-41 | Lost | 2.3853 | 0.0000 |
| 16-Sep-06 | vs Akron (84) | 24-21 | Won | -0.6527 | 0.1170 |
| 23-Sep-06 | at Eastern Michigan (109) | 24-17 | Won | -0.8474 | -0.0000 |
| 30-Sep-06 | at Kentucky (32) | 36-45 | Lost | 0.6754 | -0.5550 |
| 07-Oct-06 | at Toledo (93) | 42-20 | Won | -0.4560 | 0.3136 |
| 14-Oct-06 | vs Ball St (92) | 18-7 | Won | -0.8400 | -0.0000 |
| 19-Oct-06 | vs Bowling Green (99) | 31-14 | Won | -0.9933 | -0.0000 |
| 04-Nov-06 | at Temple (111) | 42-26 | Won | -0.9991 | -0.0000 |
| 10-Nov-06 | vs Western Michigan (60) | 31-7 | Won | -0.1627 | 0.6070 |
A red opponent rating indicates modification according to home field advantage (0.1961).