| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 02-Sep-06 | vs Wisconsin (6) | 14-35 | Lost | 1.2774 | 0.0000 |
| 09-Sep-06 | vs Buffalo (112) | 48-40 | Won | -1.4011 | 0.3961 |
| 16-Sep-06 | at Florida Int'l (119) | 33-28 | Won | -1.7372 | 0.0600 |
| 23-Sep-06 | vs Kent St (79) | 3-38 | Lost | -0.5997 | -0.8025 |
| 30-Sep-06 | at Ohio U. (44) | 21-9 | Won | 0.4498 | 1.0000 |
| 07-Oct-06 | at Ohio State (2) | 7-35 | Lost | 1.9443 | 0.0000 |
| 14-Oct-06 | vs Eastern Michigan (109) | 24-21 | Won | -1.2396 | 0.5576 |
| 19-Oct-06 | at Central Michigan (47) | 14-31 | Lost | 0.4264 | 0.0000 |
| 28-Oct-06 | at Temple (111) | 14-28 | Lost | -0.9991 | -1.0000 |
| 04-Nov-06 | at Akron (84) | 28-35 | Lost | -0.2605 | -0.4633 |
A red opponent rating indicates modification according to home field advantage (0.1961).