| Date | Opponent | Score | Result | Opp. Rating | Impact |
|---|---|---|---|---|---|
| 02-Sep-06 | vs Idaho (59) | 27-17 | Won | -0.3572 | 0.2509 |
| 09-Sep-06 | vs Eastern Michigan (103) | 52-20 | Won | -1.3884 | -0.0000 |
| 16-Sep-06 | at Pittsburgh (37) | 38-23 | Won | 0.7991 | 1.0000 |
| 23-Sep-06 | vs Notre Dame (5) | 37-40 | Lost | 1.5124 | 0.0000 |
| 30-Sep-06 | vs Illinois (83) | 20-23 | Lost | -0.7798 | -1.0000 |
| 07-Oct-06 | at Michigan (1) | 13-31 | Lost | 2.7821 | 0.0000 |
| 14-Oct-06 | vs Ohio State (2) | 7-38 | Lost | 1.8719 | 0.0000 |
| 21-Oct-06 | at Northwestern (86) | 41-38 | Won | -0.3982 | 0.2099 |
| 28-Oct-06 | at Indiana (29) | 21-46 | Lost | 1.0009 | -0.3911 |
A red opponent rating indicates modification according to home field advantage (0.2405).